Of note, the expression of genes involved in iron uptake and processing ( Tfrc , Steap3 , Slc11a2 ) or the activation of polyunsaturated fatty acids ( Lpcat , Acsl4 ) was not changed in G6pdh chon growth plates, largely excluding these pathways as inducers of ferroptosis in our model (Fig
Abbreviations MTHFR: Methylenetetrahydrofolate reductase GSTO-1: Glutathione S-transferase omega-1 ROS: Reactive oxygen species DNA: Deoxyribonucleic acid HHcy: Hyperhomocysteinemia Hcy: Homocysteine TOAST: Trial of ORG 10172 in Acute Stroke Treatment PCR: Polymerase chain reaction HWE: Hardy-Weinberg equilibrium
Linkermann A, Skouta R, Himmerkus N, Mulay SR, Dewitz C, De Zen F, et al
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