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Large meals are hard to tolerate when due to slowed gastric emptying the stomach might still be partially full from your last meal

Because of this phenomenon, older animal models were an ideal subject group for studying potential improvements brought about by paraxanthine supplementation." "However," he continued, "in younger individuals, cognition is already at its best, so seeing significant improvements to an already well-functioning system is quite surprising." This finding highlights the potential of paraxanthine as a caffeine replacement in individuals of all ages, suggesting that it may be better suited to cognition-focused supplement formulations

When would I have to wean off