Research supports what we see in our clinic certain gut bacteria can both create and break down histamine4
We conclude that melatonin, at pharmacological concentrations, induces changes in the oxidative state of HPSC
McMurray JJV, Solomon SD, Inzucchi SE, Kber L, Kosiborod MN, Martinez FA, Ponikowski P, Sabatine MS, Anand IS, Blohlvek J, Bhm M, Chiang C-E, Chopra VK, de Boer RA, Desai AS, Diez M, Drozdz J, Dukt A, Ge J, Howlett JG, Katova T, Kitakaze M, Ljungman CEA, Merkely B, Nicolau JC, OMeara E, Petrie MC, Vinh PN, Schou M, Tereshchenko S, Verma S, Held C, DeMets DL, Docherty KF, Jhund PS, Bengtsson O, Sjstrand M, Langkilde A-M
Adrenal Support: Stress, Fatigue & Pain Flares Adrenal Support may be especially helpful if you experience: Chronic fatigue or burnout related to ongoing pain Stress-triggered endometriosis flares Difficulty tolerating pain during periods of poor sleep or high stress Adaptogens and adrenal-supportive nutrients help regulate cortisol rhythms, improve stress resilience, and reduce stress-driven inflammatory amplification