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Active intestinal calcium transport in the absence of transient receptor potential vanilloid type 6 and calbindin-D9k

In vitro studies using endothelial cells stimulated by oxidized low-density lipoprotein (ox-LDL), this compound (10 M, 24 h) increased cell viability, reduced apoptosis from 23% to 19%, inhibited ICAM-1 and E-selectin mRNA expression, and enhanced antioxidant activity through increased superoxide dismutase (SOD) and glutathione peroxidase (GPX) activities while decreasing malondialdehyde (MDA) levels [2]