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The Accelerated Approval is based on part 1 of the ESSENCE trial that showed that at 72 weeks, 36.8% of people treated with Wegovy 2.4 mg achieved improvement in liver fibrosis with no worsening of steatohepatitis compared to 22.4% of individuals who received placebo

Yes, there are long-term studies on Mounjaros safety

This is significant because, if a single valid vector can be identified (see below for criteria), it demonstrates that somatic and affective symptoms have a common core and, hence, a shared pathophysiology [25]

However, it's a strong signal that the era of widely available compounded GLP-1s is ending