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Same as the above, we performed a fivefold CV on these patients as above using the pre-trained unsupervised models on the single-admission patients data to generate topic mixtures on the first admissions as input to a supervised classifier (i.e., elastic net), which then predicts the mortality in the last admission upon discharge

In terms of kinase enrichment, pathways related to cell cycle, DNA damage response, cell proliferation and regulation of cytoskeleton organization account for the effects of (M+D)/2 and (M+D+V)/3 compared to the addition of single agents (LIMK1, TESK1, P70S6K, CDK1, CDK2, CAMK4, CAMK2B) ( Figures 7C, D )

Intrinsic factor blood test results

Elsevier Health Sciences