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For instance, it may affect the metabolism of drugs that are substrates of the cytochrome P450 enzyme system, potentially altering their efficacy or toxicity

Xu Z, Qian J, Meng C, Liu Y, Ding Q, Wu H, et al

Srivastava KD, Kattan JD, Zou ZM, Li JH, Zhang L, Wallenstein S, et al

Armstrong 2014) Psoriatic Arthritis Up to 30% of psoriasis patients are diagnosed with an inflammatory joint disease called psoriatic arthritis , though many remain undiagnosed