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LRRK2 in Parkinson disease: challenges of clinical trials

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Death was confirmed by absence of pedal reflexes, followed by bilateral thoracotomy, following MU-ACUC guidelines and AVMA 2020 recommendations 53,54

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weight loss at target dose (trial data) ~6% CV risk reduction labelled Yes (T2D + CVD) Format Prefilled FlexTouch pen India price (May 2026) 5,6609,100/month DCGI-approved Yes (pre-2026) Generic competition in India n/a (innovator) Wegovy Novo Nordisk semaglutide Active molecule Semaglutide Receptor activity GLP-1 Primary indication Chronic weight management Max maintenance dose 2.4 mg weekly Avg

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Mild effects may include injection site irritation, headache, or fatigue

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