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The theoretical basis for synergy involves the concept of recovery periodization. Just as athletes periodize training loads to optimize adaptation, strategic timing of recovery modalities may enhance overall outcomes

pyramidale, high-frequency tetanization combined with depolarization could induce LTP, LTD, or lead to no changes in both tetanized and nontetanized pathways in all possible combinations (Cowan et al., Thus, initial studies demonstrate that CA1 interneurons can express long-term synaptic plasticity, which is calcium-dependent (Cowan et al., 2001) but not input-specific (McMahon and Kauer, 1997

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