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1c), highlighting the unique contribution of each PTM in illuminating AML biology

How do different PTMs of NRF2 (ubiquitination, phosphorylation, acetylation) interact and compete during cellular stress responses, and what is their hierarchical relationship in regulating NRF2 activity

doi: 10.1111/dom.14244 47 IgarashiAHansenBBLangerJTavellaFCollingsHDaviesNet al

Unfortunately, and ironically with the latest FDA restriction: Only large well-funded companies can afford FDA trials Naturally occurring peptides are hard to patent No patent = no financial incentive No incentive = no approval No approval = no legal compounding Thats the present reality, I hope this regulatory and political standstill will resolved in the coming years