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Arch Neurol 46:543548

One early study reported that GHK-Biotin: Increased the anagen/telogen ratio, indicating a higher percentage of follicles in the active growth phase Upregulated Ki-67, a marker of cell proliferation in cultured hair folliclesan early signal of increased follicular activity that may support stronger regrowth over time Resulted in visibly improved hair density and increased follicular activity in men with alopecia when applied topically at 10 ppm for four months (Active Peptide Company, 2014) These effects suggest that GHK-Biotin may help anchor hair at the root, strengthen keratin synthesis, and support regrowth, particularly when paired with other regenerative peptides

Each escalation step can temporarily increase side effects