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Retatrutide would, however, be expected to lead to more weight loss, more quickly, given both its ability to mimic three hunger-regulating hormones and the data released by Eli Lilly so far

This feature proves good for morning work, and bad for any sort of afternoon work after lunch (I get productive again right before dinner, which is annoying for dinner plans and going to sleep at a reasonable hour because I can't sleep right after eating)

What comes next Eli Lilly says it plans to launch more than six additional Phase 3 trials in 2026 to further test retatrutide across different patient groups

Nausea and vomiting are the most common, followed by diarrhea and stomach pain