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Description

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During oocyte meiosis, coordinated Ca 2+ release from the ER to mitochondria through the MAMs region is essential for Ca 2+ oscillations, which serve as key signals for cytoplasmic maturation, spindle reorganization, and chromosome alignment [64, 65]

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Upon stimulation by agents such as VEGF, the binding of eNOS and Cav-1 is released, eNOS associates with calmodulin, and then subsequently phosphorylated by heat shock protein 90 and AKT 23

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