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However, using LUXendins, GLP1R can only be studied in the non-stimulated state, precluding examination of different receptor pools or responses to clinically relevant GLP1RA
The role of GLP-1 in the nervous system remains inconclusive, yet indicates its potential for alleviating neuroinflammation, safeguarding neurons and glial cells from oxidative damage, and optimizing neurotransmitter equilibrium [83]
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Trial data suggests retatrutide produces greater weight loss than tirzepatide (24.2% vs 20.9%) or semaglutide (24.2% vs 14.9%)
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