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Some people may have difficulty getting enough B12 from diet alone, especially those with low intake of animal products, certain digestive conditions, prior weight-loss surgery, or medications that affect absorption

When an unblinded clinician rates a self-limiting condition in a cohort that has already lost a quarter of its patients, a near-universal response rate is close to the expected result whether or not the drug does anything

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The result is that millions of symptomatic women either dont receive treatment, receive suboptimal treatment, or face long wait times to see a menopause-trained specialist