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Moreover, a team at the US Mayo Clinic calls to personalize obesity treatment, using an individuals biology instead of a one-size-fits-all approach after identifying a biological subtype of obesity that responds better to one GLP-1 medication than other patients do

In June, Eli Lilly has announced Phase II results of its SYNERGY-NASH trial in which 54.9% of patients on its dual GLP-1/GIP receptor agonist tirzepatide 5 mg, 51.3% of patients on tirzepatide 10 mg and 51% of patients on tirzepatide 15 mg saw their fibrosis decreaseby at least one stage without their metabolic dysfunction-associated steatohepatitis (MASH) worsening

The second study noted unexpected deaths in several mice treated with liraglutide, possibly due to the dosage amount given