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Whilst all GLP-1 medications can cause nausea to varying degrees, evidence suggests dulaglutide (Trulicity) and once-weekly exenatide (Bydureon) tend to produce lower rates of nausea compared with other options

The titration schedule serves two purposes

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Cardiovascular and Heart Health Benefits Beyond Weight Loss The LEADER, SUSTAIN-6, and SELECT trials documented that GLP-1 medications reduce major adverse cardiovascular events (heart attack, stroke, cardiovascular death) by 2635% in patients with existing heart disease or high cardiovascular risk