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Most people describe it as the mental noise around food finally going silent

I found the article to be especially interesting when paired with another by The New York Times earlier this year: A Push for More Organ Transplants Is Putting Donors at Risk

Investigators reported that gastrointestinal effects were the most common adverse events, were generally mild to moderate, and usually occurred during the dose-escalation phase of the study

In mice bred to be deficient in mast cells, even an obesity-inducing diet doesnt cause the expected weight gain.[ref][ref] Other research, though, claims mast cells have nothing to do with obesity