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There is limited direct evidence for this specific stack in controlled studies, and clinicians considering it should weigh the additive mechanistic logic against the absence of human safety data for the combination

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However, no significant differences were found for the levels of TMAO among participants with different meat-intake frequencies (Figure S1)

RNA sequencing analysis and the use of the iron-induced cell death inhibitor ferrostatin-1 demonstrated an association between FNDC3B and ferroptosis