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These results are in line with a prospective cohort study in seven patients with psoriasis and T2DM, in which 12 weeks of liraglutide treatment significantly decreased PASI and DLQI, improved glycemic control, reduced BMI and waist circumference, and produced histological skin improvements, including reduced epidermal thickness [156]

In contrast, SGLT2 inhibitors have shown renal protective effects and may be prioritized in this group

In addition, hepatocytes have the ability to induce innate and adaptive immune defenses to dampen the inflammatory response during necrosis

Physicians report major concerns about patient education, unrealistic expectations, rising healthcare costs, supply issues for diabetes patients, and widening health inequities