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Any skin changes typically occur gradually over months of consistent use and vary significantly between individuals

One clinical trial showed that patients lost more weight if they started with a higher BMI and took topiramate for longer

Advanced protocol Experienced researchers sometimes use higher doses, though diminishing returns and increased side effect risk apply

For Blue Cross, losses are likely to continue into this year, despite the insurer eliminating jobs, deploying computer algorithms to target doctors it believes are overcharging, restricting coverage of GLP-1 drugs for weight loss, and pushing back against health care providers seeking higher reimbursement rates