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In 2021, Novo Nordisk began manufacturing Wegovy specifically for weight loss, because Ozempic is only FDA-approved for treating diabetes

found a 56% increase in iron in the caudate nucleus and a 44% increase in the putamen compared to the control group

DE Andrade IT, Gualano B, Hevia-Larrain V, Neves-Junior J, Cajueiro M, Jardim F, et al

While they showed a 2.18-point improvement (on a 7-point scale) in overall severity of illness and a reduction in depression based on one scale, they did not show improvement in depression based on another scale