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After 6 weeks of treatment, mice treated with gemcitabine, either as a single agent or in dual combination with HGF or c-MET inhibition, exhibited smaller tumours than IgG-treated controls, but statistically significant differences were only observed in G + Ci and the triple therapy (Hi + Ci + G) groups

Additionally, ROS function as signaling molecules and regulate various types of kinases and transcription factors in the initiation and development of inflammation

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