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During the latter phase of the action potential, the myocardium is very excitable and may develop arrhythmia if stimulated electrically or mechanically

Warnings and Precautions Consult a healthcare professional before use if pregnant, nursing, or taking medication

Its effects on sleep are indirect, primarily resulting from its ability to reduce pain, inflammation, and systemic stress, which are common barriers to quality rest

Chronic Signaling and Biased Agonism Emerging research suggests melanocortin receptors may exhibit ligand-dependent biased agonism capable of selectively activating intracellular pathways over time