With the medications known to reduce muscle mass, Whyte said an important question was whether this went beyond what would be expected from weight loss alone
For instance, four well-known nutraceuticals-RSV, CUR, PPR, and QUE-have been extensively studied for their protective effects on human health (Figure 1)
What the science supports is a clear mechanism for supporting mitochondrial function and insulin sensitivity, which is why MOTS-c therapy is a thoughtful tool for patients whose weight loss resistance traces back to metabolic and mitochondrial dysfunction, without artificially suppressing appetite
Final Thoughts Ultimately, the right choice depends on your personal prioritiessuch as budget, level of support, medication preferences, or flexibility