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But if the pressure drops too much or too quickly, it can result in hypotension, or low blood pressure

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Potential advantages associated with baxdrostat include: No gynecomastia reported No breast tenderness Minimal endocrine-related adverse effects Direct targeting of aldosterone excess Once-daily dosing convenience Important considerations: Hyperkalemia monitoring is still required Long-term cardiovascular outcomes are still being evaluated Cost may initially exceed generic MRAs such as spironolactone and eplerenone As hypertension management continues to evolve, it will be interesting to see where aldosterone synthase inhibition ultimately fits within future guideline-directed therapy