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Moreover, PDS5B 17A expressing cells exhibited genomic instability upon IR treatment, manifesting as an increase in chromatid breaks and radial chromosomes (Fig

-TOH administration, initiated post-SE, restored the dendritic spine density to near-control levels, suggesting that it promotes the formation of new spine rather than preventing acute loss

Mechanistically, quercetin may also enhance glucose uptake by regulating the expression and function of GLUT4 and the insulin receptor beta subunit ( FIGURE 3 On the other, hyperglycemia also induces metabolic alterations, resulting in the disturbance of protein, fat, and carbohydrate metabolism

Furthermore, cancer cells with high expression of MRP1 are sensitive to iron dependent deathinducers targeting GSH metabolism