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The new Wegovy pill, meanwhile, is approved for 25 mg daily

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According to NICE guidelines (NG28), GLP-1 receptor agonists are typically considered when triple therapy is not effective, not tolerated or contraindicated for type 2 diabetes

Indeed, although having the typical GST fold, none of the cysteine of the CPxC signature found in plant sequences is conserved in other organisms notably mammals, and there is no evidence for a cysteine involvement or for a requirement of GSH for their function