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For gastrointestinal symptoms commonly associated with GLP-1 therapy, research on specific strains (though not in GLP-1 users specifically) includes: Lactobacillus rhamnosus GG (ATCC 53103) has evidence for diarrhoea management Bifidobacterium lactis BB-12 and Bifidobacterium longum BB536 have been studied for constipation relief Lactobacillus plantarum 299v has some evidence for bloating and abdominal discomfort Colony-forming units (CFUs) indicate the number of viable bacteria per dose

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ASCO Annual Meeting Proceedings Part I Clinical Oncol 25(18S), 2007

Each one does something distinct: Pathway 1 GLP-1 Reduces appetite