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Combining it with another GLP-1 or GIP agonist (semaglutide, tirzepatide) would compound the same receptor load and the same GI and hypoglycemia risks with no efficacy evidence to support it

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32 this issue), we have extended these findings to human volunteers without obesity and further showed that the profound muscle increases induced by blocking both GDF8 and ActA in humans are also accompanied by a loss of fat

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