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Description

UPP1 facilitates the conversion of 5-FU into its active compounds, thereby enhancing its inhibitory effect on thymidylate synthase

The human results were real but modest

The detailed interrelationships and interdependencies between substances that damage the epithelial barrier, the intestinal microbiota, the immune system, the development of inflammation, changes in cell function and ultimately the development of diseases, often located distantly from the intestine, remain unclear