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Hypothesis 3 Glycemic control beyond retatrutide alone Cagrilintide adds postprandial glucagon suppression a mechanism retatrutide does not engage

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More serious but less common adverse effects observed in trials or associated with this drug class include: Increased heart rate , a class effect seen with GLP-1 receptor agonists [15] [12] Gallbladder disease , including gallstones (cholelithiasis), which has been associated with rapid weight loss and incretin-based therapies more broadly