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Third, although we focused exclusively on female patients in line with the epidemiology of lipedema, future studies should consider potential sex-specific differences and include appropriate controls for hormonal status, menopausal state, and body mass index (BMI)

STUDY OVERVIEW AND OUTCOMES Rising use of GLP-1 agonists across common orthopaedic procedures and association with improved postoperative outcomes This retrospective cohort study used a national claims database to identify patients with obesity-related diagnosis codes who underwent 10 of the most common orthopaedic surgeries from 2010 to 2023

Growing clinical evidence suggests that semaglutide may help improve cholesterol profiles, though the mechanism works primarily through weight reduction rather than direct lipid-lowering action

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