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We believe that these findings should also change the nature of the conversation about the role of obesity in HFpEF, as the Step-HFpEF results clearly indicate that obesity is not simply a comorbidity in patients with HFpEF but a root cause and a target for therapeutic intervention. The study was sponsored by Wegovy maker Novo Nordisk

In support of this finding, human studies have demonstrated positive correlations between plasma ghrelin levels and craving scores

However, you should contact your doctor promptly if you experience any of the following: Ongoing vomiting or severe abdominal pain

GPX4 is an antioxidant enzyme that primarily reduces lipid peroxides, especially lipid hydroperoxides, into their corresponding alcohols, thus protecting cell membranes from oxidative damage [39]