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This widespread insufficiency provides a logical rationale for choline supplementation: correcting a common dietary gap may help restore normal fat-processing function in the liver
methyl-B12 500 g three times per week versus 1500 g once a week for 2 weeks, in 24 patients with PN and 10 healthy volunteers
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Prescribers initiating BPC-157 in patients with Child-Pugh A or B hepatic impairment should document: (1) the clinical rationale for peptide therapy, (2) the absence of an FDA-approved alternative for the target condition, (3) baseline hepatic function with planned monitoring intervals, and (4) the patient's informed consent acknowledging the investigational nature of the therapy and the specific evidence limitations in their population
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