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Medications that facilitate reductions in alcohol use while achieving broad clinical uptake would fill a critical unmet need. The phase 2, double-blind, parallel-arm trial recruited 48 non-treatment-seeking patients with AUD at an academic medical center in the U.S

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Why Dose Splitting Might Sound Appealing But Presents Challenges When patients experience nausea, appetite loss, or gastrointestinal discomfort during dose escalation, they sometimes wonder if spreading their weekly dose across multiple injections could ease the adjustment period