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660 On the contrary, inhibition of GPX4 with specific pharmacological inhibitors or GPX4 knockdown can aggravate secondary brain injury after cerebral hemorrhage

In general, essential fatty acid deficiency (i.e., deficiency of both ALA and LA) has been observed only in patients with chronic fat malabsorption, cystic fibrosis, or those on parenteral nutrition without PUFA (86, 95) (see the article on Essential Fatty Acids)

Furthermore, the ether linkage alters lipid packing and phase behavior in membrane bilayers, which directly impacts the experimental outcomes in membrane biophysics studies [2]