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Therefore, they are nowadays recommended as first line therapy in patients with T2DM and atherosclerotic cardiovascular disease to reduce events, regardless of baseline or target HbA1c and concomitant glucose-lowering medication according to the 2023 ESC guidelines for the management of cardiovascular disease in patients with diabetes [31]

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The thigh muscle layer sits deep beneath the fat, making accidental intramuscular injection unlikely when proper technique is followed

In the following sections, we will explore why working with a healthcare provider is non-negotiable, common mistakes you should avoid, and how to maximize both the safety and the results of your treatment