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In particular, SKN increased nitric oxide production through upregulation of endothelial nitric oxide synthase and proliferator-activated receptor alpha expression, while simultaneously decreasing iNOS, COX-2, and other oxidative markers

Antioxidant supplementation can remove excess reactive oxygen species, reduce inflammation, and stabilize the oxidative-reductive environment, thereby improving skeletal muscle blood flow and oxygen utilization capacity, the researchers wrote in the study summary

GHK-Cu for Skin Health The skin benefits of GHK-Cu are perhaps its most well-known effects