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Understanding where the peptide works best helps set appropriate expectations and design effective protocols

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However, the hypothesis that the problem could arise from an exacerbated production of arginase is not explored, which consequently depletes arginine and increases ornithine, leading to a potential chain of reactions [89]

Reduced free carnitine and increased serum and urine acylcarnitine levels were also demonstrated in patients with VPA-induced Reye-like syndrome [45]