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The peptide downregulates or inhibits key lipogenic enzymes including fatty acid synthase and acetyl-CoA carboxylase, which are responsible for converting excess dietary carbohydrates and other substrates into fatty acids for storage

However, activators of this receptor also are gaining attention due to their ability to protect nerve cells from damage, promote nerve cell growth, and boost the integrity of the blood-brain-barrier, a tight, semi-permeable membrane that controls which substances in the bloodstream can get into the brain

Discontinuing glucagon-like peptide-1 receptor agonists and body habitus: A systematic review and meta-analysis

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