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Variants in GLP1R and GIPR genes often correlate with faster initial weight loss, while FTO and MC4R variants may indicate slower early progress but sustained long-term benefit
If the study had used something like the DePaul Questionnaire at baseline and in the 12- and 24-week assessments, it could have determined if people with more severe gut, skin, and allergic-type symptoms benefited from the mast cell drugs
This is the latest reported benefit of GLP1s, originally prescribed for diabetes management and now prescribed widely for obesity
doi: 10.1530/EC-18-0514 104 LengsfeldSProbstLEmaraYWerlenLVogtDRBatheltCet al
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