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Aging (Reduced Synthesis Capacity) As you age, production of glutathione declines due to: Reduced activity of gamma-glutamylcysteine ligase (GCL) , the rate-limiting enzyme in glutathione synthesis Decreased cellular energy (ATP) to fuel glutathione recycling Lower levels of precursor amino acids (especially cysteine and glycine) Studies show glutathione levels drop 10-15% per decade after age 40 [3]
in: PubMed | Google Scholar 1 Ted Rogers Centre for Heart Research, University of Toronto, Toronto, Ontario, Canada
Peptides occur naturally in the body and can also be produced synthetically
Funding This research has been funded by the generosity of the Stollery Children's Hospital Foundation and supporters of the Lois Hole Hospital for Women through the Women and Children's Health Research Institute (WCHRI Grant Application ID #: 2096), Austrian Tyrolean Cancer Research Institute (Tiroler Krebsforschungsinstitut, Innsbruck, Austria), Austrian Research Fund (Fonds zur Frderung der wissenschaftlichen Forschung, FWF), and the Saudi Cultural Bureau, Ottawa, Canada
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