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A 2021 study in published in NEJM of obese adults that used once-weekly injections found weight loss by 10% or more

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Many plans require documented failed attempts with other weight loss medications first, adding months to the treatment timeline

509 AS-252424 is a specific and targeted ACSL4 inhibitor that binds directly to the glutamine 464 of ACSL4 to inhibit its enzymatic activity, thereby inhibiting lipid peroxidation and ferroptosis, effectively alleviating ferroptosis-mediated organ damage in mouse models, including I/R-induced kidney injury and acute liver injury