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The second and third hotspot are known as the HGF chain, localized on blade five of the SEMA domain and immunoglobulin-plexin-transcription factor (IPT) homology domains 23, respectively

By decreasing the incidence of obesity-related conditions, such as obstructive sleep apnoea or heart failure with preserved ejection fraction, tirzepatide helps alleviate the burden on healthcare resources, improving outpatient appointment availability and freeing up emergency room space [9, 34, 35]

doi: 10.1111/dom.14725 Mosenzon O, Garvey WT, Hesse D, et al

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