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The peptide consists of 83 amino acids with a molecular weight of approximately 9.1 kDa, distinguished from native IGF-1 (70 amino acids) by two critical structural modifications: substitution of arginine for glutamic acid at position 3 and addition of a 13-amino acid extension at the N-terminus

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Readers should view Berberine as a potentially beneficial supplementused cautiously, not as a substitute for evidence-based medications

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