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395 The loss of double-strand repair pathway due to BRCA1 or BRCA2 mutations renders cancer cells more dependent on the PARPs-mediated repair, and more sensitive to PARP inhibition, raising a possibility of a wider application of PARPi in cancer therapy

selective nicotinamide N-methyltransferase (NNMT) inhibitor Purity: 9899% (HPLC-verified, research grade) Appearance: Off-white to pale yellow crystalline powder (salt) or reddish-brown to orange powder depending on form or salt Physical Form: Lyophilized or crystalline solid powder

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