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2021;33:833-844.e835
Dietary polyphenols have received enormous attention from scientists and nutritionists due to their well-known role in human health, because they can help to prevent degenerative diseases such as cancer, CVD, and neurological disorders [62], and their therapeutic effects are based on the regulation of cellular signaling pathways [63,64]
This leads to upregulation of pro-inflammatory cytokines and microglial activation in the hippocampus, ultimately suppressing the generation of Bromodeoxyuridine-positive/Doublecortin-positive (BrdU+/DCX+) immature neurons and Bromodeoxyuridine-positive/Neuronal Nuclei-positive (BrdU+/NeuN+) mature neurons
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