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The bioactivity results, however, showed that GLP-DARPin had a stronger blood glucose-lowering effect than GLP-2DARPin

Thats especially true of Wegovy, which is in short supply after its manufacturer, Novo Nordisk, decided to limit starter doses to ensure that anyone who starts taking the drug can continue to get it

doi: 10.1016/b978-0-12-571131-9.50017-7 13 BellGISanchez-PescadorRLaybournPJNajarianRC

Notably, while both carbohydrate and fat ingestions induce considerable increase in GIP secretion, plasma GLP-1 levels primarily surge after glucose-rich meals (56) [ Figure 1 Section A]