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Importantly, BBTMA occurs in an anaerobic environment, which suggests that it is catalyzed not by the CntA/B oxygenase, but rather by a novel oxygen-independent enzymatic pathway for the conversion of metabolites of the l-carnitine pathway to TMA

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As such, we evaluated the ability of orally delivered dihexa (2mg kg/daily) to impact water maze learning in 24 month old Sprague Dawley rats of mixed gender